Cardiac toxicity associated with overdose of intravascular injection of local anesthetic is characterized by hypotension, atrioventricular conduction delay, idioventricular rhythms, and eventual cardiovascular collapse.
2.
Atrioventricular conduction disturbances ( AV block; tertiary AV block ) may result from impaired conduction in the AV node, or anywhere below it, such as in the bundle of His.
3.
The order of the potency of the effects AH-1058 has on the cardiovascular system is : ventricular contraction > coronary blood flow > > atrioventricular conduction > sinoatrial automaticity ( level of sinoatrial self-activation ).
4.
The equivalent atrial pacing mode is AAI or AAIR which is the mode of choice when atrioventricular conduction is intact but the natural pacemaker the sinoatrial node is unreliable sinus node disease ( SND ) or sick sinus syndrome.
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